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How long does Zithromax stay in your system?|4|I finished taking Zithromax about 2 days ago for ear infections, which haven't completely healed (it happens to me) and was wondering how long it stays in your system/when it would be safest to drink some alcohol after finishing the prescription.|The half life of Zithromax is 68 hours. This means that 68 hours after your last dose, half of the drug concentration is still floating around in your bloodstream and other tissues. The reason for this long period of excretion is that a large portion of the medication is taken up by your tissues, and then slowly released back in to your blood. It is finally voided to the outside in your bile after being processed by the liver.To be safe, you should wait at least 7 days to ensure the concentration will be low enough that your liver won't be pulling double duty processing alcohol and antibiotics at the same time.|Ask a pharmacist if you wana be that careful.|try a week to two weeks just to be safe
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